Cytosolic pH is a second messenger for glucose and regulates the PKA pathway via V-ATPase
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چکیده
BY4741 (wild-type) MATa ura3∆0; leu2∆0; his3∆1; met15∆0 Openbiosystems RD66 VMA5-GFP::HIS3 Openbiosystems RD68 VPH1-GFP::HIS3 Openbiosystems RD146 VMA5-RFP::KANR This study RD157 VMA5-RFP::KANR; VPH1-GFP::HIS3 This study RD67 VMA2-GFP::HIS3 Openbiosystems RD148 VMA5-RFP::KANR This study RD151 VMA5-RFP::KANR pHluorin::URA3 This study RD57 vma5∆::KANR Openbiosystems RD152 vma5∆::KANR; pHluorin::URA3 Openbiosystems RD155 VPH1-WT::URA3; VMA5-RFP::KANR This study RD156 VPH1-D329N::URA3; VMA5-RFP::KANR This study RD105 cdc19-1ts::KANR C. Boone RD78 pgm2∆::KANR Openbiosystems RD58 ppa1∆::KANR Openbiosystems RD59 vma2∆::KANR Openbiosystems RD98 gpa2∆::NATR This study RD159 vma5∆::KANR; gpa2∆::NATR Openbiosystems RD116 pHSP12-qV-LEU2::HSP12 This study RD118 pHSP12-qV-LEU2::HSP12; vma5∆::KANR This study RD120 pHSP12-qV-LEU2::HSP12; vma2∆::KANR This study RD121 pHSP12-qV-LEU2::HSP12; gpa2∆::NATR This study RD122 pHSP12-qV-LEU2::HSP12; vma2∆::KANR; gpa2∆::NATR This study
منابع مشابه
Cytosolic pH is a second messenger for glucose and regulates the PKA pathway through V-ATPase
Thank you for submitting your manuscript for consideration by The EMBO Journal. It has now been seen by three referees whose comments to the authors are shown below. As you will see while all three referees consider the study as very interesting and potentially important they all feel that the causal link between cytoplasmic pH/V-ATPase and PKA needs to be strengthened considerably before they ...
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